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Frontline Plus & Seresto Combo

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Frontline Plus
Frontline Plus for Small Dogs up to 22lbs (Orange)
Rated 4.9/5 (318 Reviews)
Price $20.42
Seresto Collar
Seresto Collar For Small Dogs upto 18lbs - 15 inch (38 cm)
Rated 4.9/5 (112 Reviews)
Price $28.11
  • Frontline Plus for Small Dogs up to 22lbs (Orange) 3 DOSES $20.42 (x1)
  • Seresto Collar For Small Dogs upto 18lbs - 15 inch (38 cm) 1 collar $28.11 (x1)
Total $60.66 $48.53
You Saved $12.13 on this Super Combo


Frontline Plus Flea Treatment for Dogs

Frontline Plus is a remarkable monthly spot-on flea and tick treatment for dogs. It is a topical solution formulated with the active ingredient Fipronil and (S)-Methoprene. It aids in the prevention of external parasites such as adult fleas, flea eggs, flea larvae, chewing lice, and ticks in dogs. This solution is proven to kill adult fleas within 12 hours and eliminates ticks and chewing lice within 48 hours of application.

Moreover, it promotes a fast-acting and long-lasting flea and tick protection that can last up to four weeks. In a single monthly dose, it also helps to break the flea cycle and prevents re-infestations. This flea and tick treatment provides waterproof protection after 24 hours of application and is completely safe and effective to administer in dogs and puppies from 8 weeks of age and older.

Product Form: Topical (Spot-on)

Key Takeaways:

Kills adult fleas

Eliminate flea eggs & larvae, stops re-infestation

Eradicate fleas and prevent Flea Allergy Dermatitis (FAD)

Kills ticks

Kills Chewing lice

Frontline Flea Spray

Frontline Spray is a uniquely formulated flea and tick treatment for dogs, cats, puppies, and kittens. This spray formula is highly effective in eliminating flea infestations and helps in curing Flea Allergy Dermatitis (FAD) in cats and dogs. Moreover, the product provides flea protection for 4 weeks and tick protection for roughly 3 weeks. The product is also quite easy to administer in cats and dogs. For more info click Frontline Spray.

Key Benefits

  • Kills adult fleas and ticks within 2 days of application
  • Eliminates life stages for 4 continuous weeks
  • Protects pet from painful insect bites
  • Controls all kinds of ticks including the deadly ones like American dog ticks, brown ticks, deer ticks and lone star ticks
  • Protects pet from fatal tick-borne diseases like Rocky mountain fever and Lyme disease
  • Aids in treating Flea Allergy Dermatitis (FAD)
  • Waterproof treatment that keeps acting even after swimming or bathing the pet

How To Use

How to use Frontline Plus for dogs

Frontline Plus for dogs keeps your dog happy and healthy by providing effective and long-lasting flea and tick protection, killing 100% of fleas within 12 hours of treatment. To administer Frontline Plus flea treatment to your dog, follow these steps:

Frontline Plus for dogs Step One

Let the puppy or dog stand in a comfortable position. Part the fur between the shoulder blades to make the skin visible.
Frontline Plus for dogs Step Two

Invert the open pipette and place its tip onto the skin. Squeeze out the solution until the pipette is empty. Allow the area to be completely dry.
Frontline Plus for dogs Step Three

For small and medium sized dogs, apply at one spot only. For larger dogs, apply at 4-5 spots across the backbone. It is also recommended for pregnant, lactating and breeding dogs.

Follow the Dosage Chart given below for Appropriate Pack Size:
Pack Color Dog Weight Dog Size Dose Content Strength Product Page
Orange Up to 22 lbs Small Dogs 0.67 ml 9.8% of Fipronil and 8.8% of S-methoprene Click Here
Blue 23-44 lbs Medium Dogs 1.34 ml 9.8% Fipronil and 8.8% of S-methoprene Click Here
Purple 45-88 lbs Large Dogs 2.68 ml 9.8% of Fipronil and 8.8% of S-methoprene Click Here
Red 89-132 lbs Extra Large Dogs 4.02 ml 9.8% of Fipronil and 8.8% S-methoprene Click Here


  • It is formulated for dogs so do not use on any other species.
  • It is an inflammable product so store at cool and dry place.
  • Until the application site is dry, just keep away children and other pets from grooming or playing with the treated pet.
  • Keep away from the pet's eyes and mouth. Also, make sure the pet does not lick the applied area.
  • Keep away from children. If swallowed accidentally then immediately contact a poison control center.
  • In case the product enter pet's eyes then flush with lots of water.
  • Sterilize hands after treating the pet.
  • Do not drink, eat or smoke while applying the treatment.
  • Consult a veterinarian before treating aged, convalescing and debilitated pets.

More Information

Q. What is Frontline Plus?

Manufactured by Merial / Boehringer Ingelheim, Frontline Plus flea and tick for dogs is a popular flea and tick treatment that gives quick results. Suitable for 8 weeks and older puppies, the treatment kills 100% adult fleas within 12 hours and it is approved for nursing, breeding and pregnant dogs. It eradicates ticks and biting lice within 48 hours of application. Its monthly action eliminates flea eggs, larvae and pupae for a period of four weeks.

Active Ingredients Fipronil is an adulticide that kills adult fleas and ticks while S-methoprene is an Insect Growth Regulator, which curbs the juvenile life stages of fleas, and ticks. Together the ingredients give absolute protection against fleas and ticks, and prevent future occurrence of these annoying insects.

    Target Species: Dogs
    Life Stages: Puppy, Adult, Senior
    Product Type: Flea and Tick Protection
    Product Form: Topical (Spot-on)
    Pack Quantity: 3, 6 and 12 Doses

Q. How does Frontline Plus for dogs work?

Frontline Plus for dogs is made of two active components; fipronil and s-methoprene. Once applied, the formula gets spread on pet's body surface and gets stored in the sebacious glands, and fills up as and when needed and thus offers persistent protection throughout the month.

Fipronil works on the central nervous system of both fleas and ticks, causing them paralysis resulting in death. S-methoprene, on the other hand works as an insect growth regulator (IGR). Insect Growt Regulator (IGR) stops parasites from growing and prevents re-infestation.

Q. How long does Frontline Plus take to work?

Frontline Plus provides month long protection against fleas and ticks. It starts working as soon as the liquid has spread all over pet’s body. After applying, Frontline Plus kills almost all the fleas within 24 hours and ticks within 48 hours.

Q. Is it safe to use Frontline Plus?

Frontline Plus is lethal on fleas & ticks and gentle on pets. The use of Frontline Plus comes with ideal safety measures and adverse reactions are significantly infrequent. Both Frontline Plus for dogs and cats are approved for use in pregnant and lactating animals.

Q. Does Frontline Plus kill ear mites?

There isn’t enough evidence available that proves the efficacy of Frontline Plus on mites infection.

  • Fipronil
  • (S)-methoprene