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Question from Teri

I’ve always used Comfortis tablets for my dog. But found the Program tabs as a lower cost alternative. Are there any different side effects with Program Tabs as compared to Comfortis? I would rather pay more than put my dog at risk. He has also had allergies with various environmental causes (not food based causes) - we now have these under control.

Our Vet Says:

Yes there are a few differences between Comfortis and Program Plus :
-Program Plus works against fleas (Ct. felis, Ct. canis, preadult stages), and for the concurrent prevention of heartworm disease (elimination of 3rd and 4th larval stages of Dirofilaria immitis) and/or treatment of adult stages of gastrointestinal nematodes such as hookworms (Ancylostoma caninum), roundworms (Toxocara canis) and whipworms (Trichuris vulpis) in dogs.
-Confortis works against adult fleas.
If you use only Program Plus against fleas, your dog will not have protection against adult fleas. You need to use another product for protection against adult fleas. For this you can use another medicine like Capstar or a spot on medicine like Advantage, K9 Advantix etc.
I will give some information about the side effects of Program Plus:
In heartworm risk regions, or if it is known that a dog has been travelling to and from heartworm risk regions, before commencing PROGRAM PLUS treatment as with any other heartworm preventive, a veterinary consultation is advised to exclude the presence of any concurrent infestation of Dirofilaria immitis. In the case of a positive diagnosis, adulticidal therapy is indicated before administering PROGRAM PLUS.
Pale mucous membranes and increased intestinal peristalsis have been observed in some dogs after treatment. The treatment of dogs with a high number of circulating microfilariae can sometimes lead to the appearance of moderate and transitory hypersensitivity reactions, such as pale mucous membranes, vomiting, laboured breathing, or excessive salivation. These reactions are associated with the release of proteins from dead or dying microfilariae and are not a direct toxic effect of the product.
If you notice any other side effects, please inform your veterinary surgeon.
For animal treatment only.
Please read the information enclosed with the product.


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On your site you sell both FRONTLINE PLUS FOR CATS and FRONTLINE TOP SPOT. Can you please explain the difference so I know which to purchase...?

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