Frontline Plus is called Frontline Combo in the U.K. but contain the same active
Frontline Combo has been approved for sale in the UK by the Veterinary Medicines Directorate.
The US equivalent of this product has been approved for sale by the EPA.
Both the UK and US products contain the same active ingredients, Fipronil & (S)-Methoprene.
The UK packaging does not have EPA approval.
If swallowed call a poison control center or doctor immediately for treatment advice. For hazards to domestic animals the 24 hour assistance line within the U.S.A. is 1-800-660-1842.
The Product Information Schedule above indicates some of the material differences between the UK and U.S.A. versions.
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I have alwaysused topical flea products non Cloey ever since she nwas old enough. This last summer I used Advantage and within about three weeks I had to put it on Cloey again. I found two types of fleas on her some were real teeny black ones and some were nbigger brown ones. The flea stuff worked for only 3 weeks on these fleas. when I used to buy it it used to say on the box works for up to three months and it DID. Have the companies watered the product down so that I have to buy it more...?
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